Malonate ester hydrolysis and decarboxylation is a typical route to synthesize what kind of chain?

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Multiple Choice

Malonate ester hydrolysis and decarboxylation is a typical route to synthesize what kind of chain?

Explanation:
Malonate ester synthesis extends a carbon chain by one atom and introduces a terminal carboxyl group. The methylene of malonate is deprotonated and alkylated with an alkyl halide, adding the R group to the malonate skeleton. After hydrolysis of the esters and decarboxylation, one carboxyl group remains, yielding a product of the form R–CH2–CO2H. So you end up with an alkyl chain extended by one carbon that ends in a carboxyl group. This is why the route is described as building an extended alkyl chain with a terminal carboxyl.

Malonate ester synthesis extends a carbon chain by one atom and introduces a terminal carboxyl group. The methylene of malonate is deprotonated and alkylated with an alkyl halide, adding the R group to the malonate skeleton. After hydrolysis of the esters and decarboxylation, one carboxyl group remains, yielding a product of the form R–CH2–CO2H. So you end up with an alkyl chain extended by one carbon that ends in a carboxyl group. This is why the route is described as building an extended alkyl chain with a terminal carboxyl.

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